▎ 摘　　要

NOVELTY - Targeting gene carrier material based on graphene, which is functionalized graphene oxide modified by folic acid and polyethylene glycol conjugate aminated with aromatic conjugated system molecule of methylated pyrene hydrochloride, where amino acid after porphyrin or doxorubicin hydrochloride is used as the carrier, loading gene small interfering RNA (siRNA) molecule or DNA, folic acid, polyethylene glycol, graphite oxide and amination with mass ratio of the aromatic conjugated system: 1:2-100:2-20:0.01-100, is new. USE - The gene carrier material is used for preparing medicine for treating tumor (claimed). ADVANTAGE - The carrier material provides high expression and good targeting activity against tumor cell. DETAILED DESCRIPTION - Targeting gene carrier material based on graphene, which is functionalized graphene oxide modified by folic acid and polyethylene glycol conjugate aminated with aromatic conjugated system molecule of methylated pyrene hydrochloride, where amino acid after porphyrin or doxorubicin hydrochloride is used as the carrier, loading gene small interfering RNA (siRNA) molecule or DNA, folic acid, polyethylene glycol, graphite oxide and amination with mass ratio of the aromatic conjugated system: 1:2-100:2-20:0.01-100, the preparation method is as follows: mixing folic acid and amino terminated polyethylene glycol mixed stirring reaction in the mixed solvent of N,N-dimethyl sulfoxide and water, evaporating the condensate by glucan gel column, folic acid and polyethylene glycol conjugate and freeze-dried in the presence of a dehydrating agent and oxidized graphite alkene ultrasonic agitation reaction, separating and washing product and amination molecules stirring reaction to aromatic conjugated system, adjusting the pH value is 1 to 3, separating and washing product to obtain positively charged functional graphene oxide that is dispersed in water or culture medium RPMI1640 with gene molecule, the host egg is incubated; the gene molecule is 0.5 to 50 wt.%, is new. An INDEPENDENT CLAIM is a method for preparing targeting gene carrier material based on graphene.