• 专利标题:   Preparing porous artificial skin receptor, comprises grinding graphene, adding nitric acid solution to boil, centrifuging, washing, taking part of centrifuged graphene, and drying to determine measured concentration,.
  • 专利号:   CN107376006-A
  • 发明人:   WAN J, WANG J, HU Z, WANG B, PENG Z
  • 专利权人:   UNIV ZHEJIANG SCI TECH
  • 国际专利分类:   A61L027/08, A61L027/30, A61L027/50, A61L027/56, A61L027/60
  • 专利详细信息:   CN107376006-A 24 Nov 2017 A61L-027/08 201806 Pages: 7 Chinese
  • 申请详细信息:   CN107376006-A CN10626794 28 Jul 2017
  • 优先权号:   CN10626794

▎ 摘  要

NOVELTY - Preparing porous artificial skin receptor, comprises (i) grinding graphene, crushing, adding nitric acid solution to boil, centrifuging and washing; (ii) taking part of centrifuged graphene, drying to determine the measured concentration, adding remaining graphene to de-ionized water to prepare solution according to measured concentration, and (iii) dissolving polyester particle in concentrated sulfuric acid, allowing stand; (iv) adding n-hexane, deionized water, and fatty alcohol polyoxyethylene ether and polyethylene glycol 400 into three-necked flask, and stirring. USE - The method is useful for preparing porous artificial skin receptor (claimed). ADVANTAGE - The receptor: has good porosity, permeability, excellent conductivity, electrochemical sensitivity, toughness, strength and tensile properties. DETAILED DESCRIPTION - Preparing porous artificial skin receptor, comprises (i) grinding graphene, crushing, adding nitric acid solution to boil for 20-60 minutes, centrifuging and washing; (ii) taking part of centrifuged graphene, drying to determine the measured concentration, adding remaining graphene to de-ionized water to prepare solution according to the measured concentration, (iii) dissolving 2-5 g polyester particle in 90-110 ml concentrated sulfuric acid, allowing stand at dark, until the polyester is completely dissolved; (iv) adding 150-250 ml n-hexane, 100-200 ml deionized water, and 5-10 ml fatty alcohol polyoxyethylene ether and 2-4 ml polyethylene glycol 400 (PEG-400) into three-necked flask, and rapid stirring to make an inverse emulsion system; (v) dropping prepared polyester solution into emulsion under stirring, after completely adding, stopping stirring, allowing to stand, centrifuging the suspension, and neutralizing with sodium hydroxide, (vi) adding deionized water to neutralized suspension, centrifuging for 3-5 times until there is no sulfate ion in the supernatant, adding water to the lower layer and freeze-drying to obtain micron-sized polyester microsphere; (vii) preparing polyester microspheres into solution of 0.1-0.5 g/l, mixing the graphene with the polyester microsphere solution, ultrasonically dispersing, carrying spin coating method to obtain graphene-polyester composite film, and drying to obtain conductive layer; (viii) treating the graphene-polyester composite membrane with 20-50 ml hydrochloric acid solution (0.1-1 mol/l) for 10-20 minutes, immersing composite membrane in phenol-tetrachloroethane solvent in a volume ratio of 0.8-1.2:1, and allowing to stand to dissolve the polyester; (ix) passing dried film through hydrazine gas at 110-130 degrees C to reduce the graphene in the film into reduce graphene; and (x) plating silver film on the reduced graphene film by using vapor deposition method to obtain porous artificial skin receptors.