• 专利标题:   Fabricating sensing device for DNA sequencing and biomolecule characterization by dicing portion of monolayer graphene sheet, converting graphene microribbon to graphene nanoribbon, and converting graphene nanoribbon to carbyne.
  • 专利号:   US2021253420-A1
  • 发明人:   SEIWERT T, MA B, TUNG S
  • 专利权人:   SEIWERT T, MA B, TUNG S
  • 国际专利分类:   B81C003/00, C12Q001/6869, B32B007/12, B32B007/02, B81C001/00
  • 专利详细信息:   US2021253420-A1 19 Aug 2021 B81C-001/00 202186 English
  • 申请详细信息:   US2021253420-A1 US173839 11 Feb 2021
  • 优先权号:   US975894P, US173839

▎ 摘  要

NOVELTY - Fabricating a sensing device for DNA sequencing and biomolecule characterization involves fabricating a microelectrode chip comprising a silicon substrate and a silicon nitride diaphragm; attaching a monolayer graphene sheet to the silicon nitride diaphragm; dicing a portion of the monolayer graphene sheet to form a graphene microribbon; converting the graphene microribbon to a graphene nanoribbon; and converting the graphene nanoribbon to a carbyne. USE - The method is useful for fabricating sensing device for DNA sequencing and biomolecule characterization (claimed). ADVANTAGE - The method utilizes a combination of mechanical dicing, atomic force microscopy (AFM) nanolithography, and transmission electron microscopy (TEM) irradiation to achieve a one-dimensional nanowire sensor to maximize the spatial resolution in DNA sequencing with the ultimate goal of achieving single-base accuracy. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a sensing device for DNA sequencing and biomolecule characterization comprising: a silicon substrate; a cavity in the silicon substrate covered by a silicon nitride layer; microelectrodes attached to the silicon nitride layer; graphene covering the microelectrodes; and carbyne attached to a portion of the silicon nitride layer covering the cavity.