• 专利标题:   Medical device used for detecting aldehyde and ketone-bearing analytes, comprises graphene varactor comprising graphene layer, and self-assembled monolayer provided on outer surface of graphene layer through electrostatic interactions.
  • 专利号:   WO2022197521-A1, US2022304589-A1
  • 发明人:   TROUDT B K, BUHLMANN P P J, KOESTER S J, ZHEN X, KOESTER S
  • 专利权人:   UNIV MINNESOTA, BOSTON SCI SCIMED INC, BOSTON SCI SCIMED INC, UNIV MINNESOTA
  • 国际专利分类:   G01N027/12, G01N027/22, G01N027/414, A61B005/05, A61B005/08, B05D001/00, C01B032/194
  • 专利详细信息:   WO2022197521-A1 22 Sep 2022 G01N-027/12 202289 Pages: 71 English
  • 申请详细信息:   WO2022197521-A1 WOUS019728 10 Mar 2022
  • 优先权号:   US161640P, US689760

▎ 摘  要

NOVELTY - A medical device consists of a graphene varactor (100) having a graphene layer (108a,108b) and a self-assembled monolayer comprising a compound(s) (C) containing hydrazine group(s) or hydroxylamine group(s), substituted hydrazine or hydroxylamine group(s), or their derivatives, provided on an outer surface of the graphene layer through electrostatic interactions between a partial positive charge on hydrogen atoms of hydrocarbon(s) of the self-assembled monolayer and a p-electron system of graphene. USE - Medical device is used for detecting aldehyde/ketone-bearing analytes in gaseous samples collected from patients during detection of diseases e.g. diabetic ketoacidosis. ADVANTAGE - The medical device has high sensitivity, and provides accurate detection of aldehyde and ketone-bearing analytes, thus allowing clinicians to provide appropriate therapeutic interventions, and hence leading to better treatment outcomes. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for modification of graphene surface for forming graphene varactor. DESCRIPTION OF DRAWING(S) - The drawing shows the schematic perspective view of graphene varactor. 100Graphene varactor 102Insulator layer 104Gate electrode 108a,108bGraphene layers 110Contact electrode