▎ 摘　　要

NOVELTY - Targeted anti-tumor gene drug delivery system graphene oxide-chitosan-anti-epithelial cellular adhesion molecule/small interfering RNA (GCE-siRNA). USE - The targeted anti-tumor gene drug delivery system is useful for preparing drugs for inhibiting tumor (claimed) e.g. human breast cancer MCF-7 by silencing survivin gene, down-regulating survivin protein expression, inhibiting tumor cell proliferation, invasion and migration, and promoting tumor cell apoptosis and its cell cycle. ADVANTAGE - The targeted anti-tumor gene drug delivery system is safe on blood and tissues. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for preparing the targeted anti-tumor gene drug delivery system, comprising mixing gene delivery carrier GCE and anti-tumor gene survivin-siRNA in a mass ratio of 30:1 at room temperature, and allowing to stand at room temperature to obtain GCE/siRNA.