• 专利标题:   Polymer bone scaffold containing in-situ growth magnetic nano-particle-containing graphene, comprises polymer matrix and graphene oxide-ferrous ferric oxide, which realizes synergistic strengthening of mechanical performance of bone scaffold and magnetic stimulation function of cell response.
  • 专利号:   CN115245602-A
  • 发明人:   UNANNOUNCED I
  • 专利权人:   UNIV SHAOYANG
  • 国际专利分类:   A61L027/44, A61L027/50
  • 专利详细信息:   CN115245602-A 28 Oct 2022 A61L-027/44 202309 Chinese
  • 申请详细信息:   CN115245602-A CN11568174 21 Dec 2021
  • 优先权号:   CN11568174

▎ 摘  要

NOVELTY - Polymer bone scaffold containing in-situ growth magnetic nano-particle-containing graphene (GO-Fe3O4), comprises a polymer matrix and GO-Fe3O4. The Fe3O4 is in-situ growing on surface of graphene oxide (GO). The combination of the two realizes the synergistic strengthening of the mechanical performance of the polymer bone scaffold and the magnetic stimulation function of the cell response. USE - Polymer bone scaffold containing in-situ growth magnetic nano-particle-containing graphene. ADVANTAGE - The polymer bone scaffold uses the in situ growth technology to obtain magnetic nanoparticles on GO, Fe3O4, endows the bone scaffold with magnetic stimulation function and enhances mechanical properties. The composition and structure are designed reasonably, and provides a new approach for stimulating bone regeneration under a magnetic field. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for preparing polymer bone scaffold, which involves: preparing GO-Fe3O4 powder and polymer powder, in which the proportion of GO-Fe3O4 is 5-15 wt.%, and then laser sintering after uniform mixing to obtain composite bone scaffold, where laser power is controlled to be 2-4 W, the scanning speed is 80-120 mm/min, the spot diameter is 50-100 µm, the scanning spacing is 0.5-1.0 mm, and the powder thickness is 100-200 µm.