• 专利标题:   Label-free immunosensor useful for detecting prostate specific antigen, comprises carbon electrode, and three-dimensional graphene-gold complexes coupled with carbon electrode and prostate-specific antigen-monoclonal antibody.
  • 专利号:   KR1589922-B1
  • 发明人:   JANG H D, CHANG H, KIM S K
  • 专利权人:   KIGAM KOREA INST GEOSCIENCE MINERAL
  • 国际专利分类:   C12Q001/68, G01N027/06, G01N033/531
  • 专利详细信息:   KR1589922-B1 02 Feb 2016 C12Q-001/68 201623 Pages: 16 English
  • 申请详细信息:   KR1589922-B1 KR138035 14 Oct 2014
  • 优先权号:   KR138035

▎ 摘  要

NOVELTY - Label-free immunosensor comprises carbon electrodes, three-dimensional graphene-gold complex coupled between carbon electrodes, and three-dimensional graphene-gold complex coupled with prostate-specific antigen-monoclonal antibody, where the three-dimensional graphene-gold complex is formed by depositing gold nanoparticles with spherical shape on surface of several graphene. USE - The label-free immunosensor is useful for detecting prostate specific antigen (claimed). ADVANTAGE - The label-free immunosensor detects prostate specific antigen with improved selectivity, specificity and sensitivity. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for method for producing the label-free immunosensor, which involves preparing a mixture comprising graphene oxide and gold precursor, performing aerosol spray pyrolysis method using the mixture to obtain three-dimensional graphene-gold complex, and coupling the three-dimensional graphene-gold complex on the carbon electrode and prostate-specific antigen-monoclonal antibody.