▎ 摘　　要

NOVELTY - Preparation of implantable electrically-stimulated conductive stent involves: (S1) preparing poly lactic-co-glycolic acid (PLGA)-graphene conductive ink by preparing aqueous dispersion of graphene using graphene, a surfactant, a plasticizer and a solvent, adding to a mixed solution of a degradable polymer and solvent, fully mixing the mixture, heating, centrifuging and defoaming, and preparing PLGA-hexagonal boron nitride (hBN) non-conductive ink by preparing aqueous dispersion of graphene using hBN powder and surfactant, then adding to mixed solution of a degradable polymer and solvent, fully mixing, heating, centrifuging and defoaming; (S2) designing different electric field distributions through selection and layer-by-layer stacking of conductive and non-conductive inks; and (S3) printing a conductive support by using conductive and non-conductive inks through a direct extrusion type double-nozzle three-dimensional printer according to designed electric field distribution. USE - The method is useful for preparing implantable electrically-stimulated conductive stent (claimed) used for coupling biotissue with different mechanical properties and repairing various portions of organism including bone, nerve, blood vessel, muscle, tendon, skin, bile duct, lymph, esophagus, trachea, intestine and uterus. ADVANTAGE - The method is simple, and ensures high material utilization rate and low loss without post-processing. The mixed printing of two inks with different mechanical properties can achieve preparation of bracket with excellent mechanical strength. The conductive bracket can meet customized electrical stimulation requirement. DETAILED DESCRIPTION - Preparation of implantable electrically-stimulated conductive stent involves: (S1) preparing poly lactic-co-glycolic acid (PLGA)-graphene conductive ink by preparing aqueous dispersion of graphene using graphene, a surfactant, a plasticizer and a solvent, adding to a mixed solution of a degradable polymer and solvent, fully and uniformly mixing the mixture, heating the mixture to a viscosity suitable for printing, centrifuging and defoaming, and preparing PLGA-hexagonal boron nitride (hBN) non-conductive ink by preparing aqueous dispersion of graphene using hBN powder, a surfactant and a solvent, then adding to mixed solution of a degradable polymer and solvent, fully and uniformly mixing the mixture, heating the mixture to a viscosity suitable for printing, centrifuging, and defoaming; (S2) designing different electric field distributions through selection and layer-by-layer stacking of conductive ink and non-conductive ink; and (S3) printing a conductive support by using conductive ink and non-conductive ink through a direct extrusion type double-nozzle three-dimensional printer according to the designed electric field distribution.