• 专利标题:   Synthesizing antibacterial aldehyde magnetic material graphene oxide compounds used e.g. for photothermal killing of bacteria, comprises reduction and functionalization of graphene oxide with magnetic material and modifying aldehyde.
  • 专利号:   US2016270403-A1, US9961902-B2
  • 发明人:   LING Y, WU M
  • 专利权人:   UNIV NAT TSINGHUA, UNIV NAT TSINGHUA
  • 国际专利分类:   A01N055/02, A61L002/08, C07F015/02, A01N035/10
  • 专利详细信息:   US2016270403-A1 22 Sep 2016 A01N-055/02 201663 Pages: 14 English
  • 申请详细信息:   US2016270403-A1 US076157 21 Mar 2016
  • 优先权号:   TW123168

▎ 摘  要

NOVELTY - Synthesizing an antibacterial material aldehyde magnetic material graphene oxide compounds (I), comprises synthesizing a graphene oxide, performing simultaneous reduction and functionalization with a magnetic material, and modifying an aldehyde onto the surface of the magnetic material. USE - The process is useful for synthesizing (I), which is used: for photothermal killing of bacteria by converting light irradiation to emit heat (claimed), where the bacteria is gram positive comprising Staphylococcus aureus or gram negative bacterial comprising Escherichia coli; and in biomedical, health care or environmental cleaning. No biological data given. ADVANTAGE - The process: provides (I) having low cytotoxicity and reproducibility; and provides (I), which can be attracted by a magnet to move or aggregate easily for further reusability. DETAILED DESCRIPTION - Synthesizing an antibacterial material aldehyde magnetic material graphene oxide compounds of formula (I), comprises synthesizing a graphene oxide, performing simultaneous reduction and functionalization with a magnetic material, and modifying an aldehyde onto the surface of the magnetic material. R = aldehyde, di-aldehyde or multi-aldehyde, preferably glutaraldehyde, vancomycin or deptomycin; M = magnetic material; and G = reduced graphene oxide. An INDEPENDENT CLAIM is also included for using (I), comprising interacting (I) with bacteria, thus capturing the bacteria with (I), and irradiating (I) and captured bacteria with a light source.