• 专利标题:   On-chip graphene electrode platform device for detecting e.g. biological targets to treat kidney diseases in patient, has on-chip electrode platform placed on substrate and provided with three dimensional laser scribed graphene electrode.
  • 专利号:   WO2018015884-A1, EP3488236-A1
  • 发明人:   NAYAK P, ALSHAREEF H N, BAEUMNER A J, DUERKOP A, FENZL C, HIRSCH T
  • 专利权人:   UNIV KING ABDULLAH SCI TECHNOLOGY, UNIV REGENSBURG, UNIV KING ABDULLAH SCI TECHNOLOGY, UNIV REGENSBURG
  • 国际专利分类:   G01N027/327, G01N033/50
  • 专利详细信息:   WO2018015884-A1 25 Jan 2018 G01N-027/327 201810 Pages: 47 English
  • 申请详细信息:   WO2018015884-A1 WOIB054337 18 Jul 2017
  • 优先权号:   US364917P

▎ 摘  要

NOVELTY - The device has an on-chip electrode platform placed on a substrate and provided with a three-dimensional laser scribed graphene electrode that has a self-standing macro/mesoporous three dimensional morphology, a three dimensional laser scribed graphene counter electrode and a three dimensional laser scribed graphene working electrode. The working electrode includes metal nanoparticles placed on a three-dimensional laser scribed graphene surface. A targeting agent is attached to the three-dimensional laser scribed graphene surface of the working electrode. USE - On-chip graphene electrode platform device for detecting biological targets to treat neurological disorders e.g. Parkinson's disease and schizophrenia, hyperuricemia and kidney diseases in a patient. Uses include but are not limited to polypeptides, polynucleotides, lipids, fatty acids, glycoproteins, carbohydrates, fatty acids, enzymes, fatty esters, macromolecular polypeptide complexes, vitamins, co-factors, whole cells, eukaryotic cells, prokaryotic cells, micelles, microorganisms i.e. viruses, bacteria, protozoa, archaea, fungi, algae, spores, apicomplexan, trematodes, nematodes and mycoplasma. ADVANTAGE - The device allows laser scribed graphene electrode based electrode patterns to exhibit improved electrocatalytic performance toward oxidation of ascorbic acid, dopamine and uric acid and high sensitivity, selectivity in a wide concentration range. The device has a high electrochemically active surface area, efficient charge transfer behavior and high repeatability of electrode material, provides laser scribed graphene electrodes that are used as a potential electrode material for different bio-analyte detection in broad range, and is utilized in large scale commercialization for practical application. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for a method for making an on-chip electrode platform. DESCRIPTION OF DRAWING(S) - The drawing shows a schematic view of a structure illustrating fabrication of a laser scribed graphene and platinum/laser scribed graphene electrode pattern on a sheet and fabrication of arrays of electrodes on polyimide sheet by laser scribing.