• 专利标题:   Preparation of composite nanomaterial, e.g. for computed tomography contrast agent, by dispersing nano graphene oxide in alcohol, adding bismuth source and selenium source, adding polyvinylpyrrolidone, and performing solvothermal reaction.
  • 专利号:   CN103736106-A, CN103736106-B
  • 发明人:   YANG Y, YANG S, ZENG B, WU H
  • 专利权人:   UNIV SHANGHAI NORMAL
  • 国际专利分类:   A61K041/00, A61K049/04, A61P035/00, C01B031/04
  • 专利详细信息:   CN103736106-A 23 Apr 2014 A61K-049/04 201442 Pages: 12 Chinese
  • 申请详细信息:   CN103736106-A CN10613024 26 Nov 2013
  • 优先权号:   CN10613024

▎ 摘  要

NOVELTY - A graphene oxide/bismuth selenide/polyvinylpyrrolidone composite nanomaterial is prepared by dispersing nano graphene oxide in alcohol, then adding bismuth source and selenium source, adding anhydrous sodium sulfite and polyvinylpyrrolidone, and performing solvothermal reaction for 1-2 hours at 180-220 degrees C to obtain the composite nanomaterial. USE - Method of preparing graphene oxide/bismuth selenide/polyvinylpyrrolidone composite nanomaterial used in preparing near-infrared photothermal cancer therapy reagent and computed tomography (CT) contrast agent (claimed). ADVANTAGE - The method utilizes easy to obtain raw material, has simple operation and low cost, and is suitable for industrial production. The obtained composite nanomaterial has high photothermal conversion efficiency and provides good CT imaging. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a graphene oxide/bismuth selenide/PVP composite nanomaterial.