• 专利标题:   Antibacterial absorbable suture comprises polyglycolic acid nanomaterial comprising graphene oxide, polyethylene glycol, chloroacetic acid, triethylamine, and organic solvent, chitosan, polyethylene glycol, cinnamon oil and mannitol.
  • 专利号:   CN111760065-A
  • 发明人:   ZHANG S, ZHANG Y, SHI X, GAO H, WANG F, PENG D, ZHANG F, MU Q, LI J
  • 专利权人:   NEW MATERIALS INST SHANDONG ACAD SCI, SHANDONG BODA MEDICAL PROD CO LTD
  • 国际专利分类:   A61L017/00, A61L017/04, A61L017/10, A61L017/12, D01F001/10, D01F008/14, D01F008/16, D01F008/18
  • 专利详细信息:   CN111760065-A 13 Oct 2020 A61L-017/10 202092 Pages: 8 Chinese
  • 申请详细信息:   CN111760065-A CN10456533 26 May 2020
  • 优先权号:   CN10456533

▎ 摘  要

NOVELTY - An antibacterial absorbable suture comprises 80-100 parts mass polyglycolic acid nanomaterial, 15-25 parts mass chitosan, 3-5 parts mass polyethylene glycol, 2-3 parts mass cinnamon oil and 2-3 parts mass mannitol. The polyglycolic acid nanomaterial is prepared by mixing graphene oxide, polyethylene glycol and organic solvent, ultrasonically dispersing to obtain dispersion, adding dispersion to organic solvent of chloroacetic acid, stirring to obtain mixed solution, dripping organic solvent of triethylamine to mixed solution at low temperature, gradually raising temperature, refluxing, concentrating to remove solvent to obtain mixture, washing with alcohol compound to obtain crude product and blow-drying. USE - Antibacterial absorbable suture. ADVANTAGE - The absorbable suture has high tensile strength, firm knotting, excellent biocompatibility, no adverse reactions in human body and long-lasting antibacterial property. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for preparation of the antibacterial absorbable suture, which involves using above raw materials and 250-350 mg/L ethylene oxide.