国家/地区 中国（11） 世界知识产权组织（5） 欧洲专利局（EPO）（3） 韩国（3） 美国（3） 日本（2）
IPC部 C（16）
IPC大类 C12（16）
IPC小类 C12N（16） C01B（5） A61K（4）
C12M（4） A61P（3） C12Q（3）
A61L（2） A61N（2） C08J（2）
G01N（2）
IPC C12N013/00（16）
发明人 CHANG L（2） GAO H（2） GUO Z（2）
HU S（2） LIU H（2） LIU Z（2）
SUN C（2）
公开年 2021（4） 2022（4） 2015（2） 2018（2） 2020（2）
申请年 2022（5）  2021（3）  2018（2）  2020（2） 
专利权人 UNIV JINAN（2）

Producing nerve cell, useful as cell therapy agent and composition for preventing and treating cranial nerve disease, comprises applying electromagnetic field to graphene structure in contact with cell to reprogram cell into nerve cell.

KIM J P, JANG Y

Generating cell-free regions in a cellular aggregate using label-free magnetic manipulation comprises suspending cells in a paramagnetic culture medium, seeding the cells and medium into microwells, and placing the microwells over array.

GUPTA T, SAHU R P, PURI I K

Use of graphene irradiation in improving insulin activity in vitro.

LU G, FENG C, ZHANG Y, FENG B, MU X, ZHANG M, HU G, ZHANG Q

Preparing graphene film in stem cell proliferation and maintaining dry cell dry, involves using methane, hydrogen and argon to prepare nanoscale graphene layer on substrate by chemical vapor deposition method to obtain nanoscale graphene-substrate, and adding polydimethylsiloxane dropwise.

CHANG L, LIU Z, GAO H, GUO Z, LIU H, HU S, SUN C

Inducing neural differentiation of mesenchymal stem cell based on electromagnetic induction involves inoculating mesenchymal stem cells on graphene film, adding mesenchymal stem cell proliferation medium to obtain culture system, and placing system in induction device containing permanent magnet.

CHANG L, LIU Z, HU S, GAO H, LIU H, GUO Z, SUN C

Microfluidic chip based on dielectric deterministic displacement useful in device for sorting cell, comprises micro flow channel having sample inlet, straight channel and two sample outlets, and three groups of electrode array pairs.

MA B, DIAO Z, WANG X, XU J

Magnetic stimulating material useful for promoting directed transdifferentiation of Muller cells in eye and in preparing material for promoting retinal ganglion cell repair, obtained by co-precipitation of functionalized graphene with hydrophilicity and biocompatibility and magnetic nanoparticles.

ZHANG W, YE S, LU W, YAN L, LIU Y

Preparing shape memory composite material with both electrical and temperature response used as cell immobilization carrier in fermentation production of L-lysine comprises e.g. mixing thermoplastic polyurethane and two-dimensional graphene.

YING H, SHA Y, ZHUANG W, ZHU C, LI M, OUYANG P, CHEN Y, LIU D, SHEN T, TAN Z

Composite material useful for delivering and desorbing macromolecular substance, preferably polysaccharide molecule, protein, DNA and RNA in cell, comprises carbon nanotube as nano-particles and polydimethylsiloxane as flexible substrate.

CHEN H, WANG L, TANG H

Preparing three-dimensional annular cell scaffold for culturing cells, by using chemical vapor deposition to grow graphene on copper/nickel template, or blending conductive material and fiber, or printing conductive hydrogel and/or aerogel.

CHENG G, HAN F, MA X, HAO Y