国家/地区 中国（8） 世界知识产权组织（5） 印度（4） 美国（2）
IPC部 C（18）
IPC大类 C12（18） G01（15） A61（4）
G16（3） B01（2） B03（2）
B82（2） G06（2）
IPC小类 C12Q（18）
IPC C12Q001/6886（18）
发明人 GARDNER L（2） HADJIDEMETRIOU M（2） HE M（2）
KOSTARELOS K（2）
公开年 2022（10） 2021（5） 2023（2）
申请年 2021（8）  2022（5）  2019（2）  2023（2） 
专利权人 UNIV KANSAS（2） UNIV KANSAS .（2） UNIV MANCHES.（2）

Electro chemiluminescence sensor based on carbon dots and gold-silver sulfide resonance energy transfer to detect promyelocytic leukemia/retinoic acid receptor alpha fusion gene in acute and early young particle, comprises carbon dot as donor, gold-silver sulfide core-shell nanoparticle as acceptor.

ZHANG Y, HAN S, ZHANG Z, LIN M, LIU A, LEI Y

Electrochemiluminescence detection kit useful in preparing detection reagent for detecting lung cancer, preferably non-small cell lung cancer, comprises gold electrode, hairpin DNA, 6-Mercapto-1-hexanol, 3-mercaptopropionic acid-N-hydroxysuccinimide ester, tris(2-dimethylaminoethyl)amine and eosin Y.

YANG H, SUN Y, CHENG D, KANG L, MA L

Electrochemical biosensor/system used to detect breast cancer from serum sample comprises platinum wire as counter electrode, silver chloride saturated with potassium chloride a reference electrode, and indium tin oxide as working electrode.

SRIVASTAVA S, PANDEY A

Three-dimensional graphene/silver nanoparticle composite nano-tag material for performing electrochemical sensing detection method of long non-coding RNA molecules, is obtained by depositing three-dimensional graphene and silver nanoparticles jointly on substrate.

WU D, YANG Y, ZHANG T, XU Y, CHEN M

Optical fiber miRNA sensor based on the gold nanoparticle coated with graphene oxide for quantitative detection of RNA, comprises broadband light source, Y-shaped optical fiber, optical fiber probe, spectrometer.

ZENG S, LUO Z, PAN Z, DING L, XU B

Detecting prostate cancer exosomal microRNA based on controllable near-infrared light-mediated phase change sol droplet digital polymerase chain reaction technology, comprises e.g. developing laser controllable output module, preparing microspheres, and detecting microRNA markers.

YU J, SHANG L, YE F, ZHANG L, ZHAO Y

Kit useful for detecting pancreatic cancer prognosis conditioncomprises upstream and downstream primer sequences of miRNA.

LIU Y, LI X, GONG X

Composition used to isolate extracellular vesicle, comprises many magnetic particles, each magnetic particle comprising core particle and targeting moiety extending from the core particle via photocleavable linker.

HE M

Identifying cell free nucleic acid in bio-fluid for diagnosing or monitoring or detecting disease state in subject, such as cancer disease, involves contacting nanoparticles with bio-fluid of subject, isolating nanoparticles, and analyzing.

HADJIDEMETRIOU M, KOSTARELOS K, GARDNER L

Identifying biomarkers from distinct biomolecule classes in biofluid by contacting nanoparticles with biofluid to allow biomolecule corona to form on surface of nanoparticles, isolating nanoparticles and surface-bound biomolecule corona, and analyzing biomolecule corona to identify biomarkers.

HADJIDEMETRIOU M, KOSTARELOS K, GARDNER L, PAPAFILIPPOU L