国家/地区 中国（42）
IPC部 C（42）
IPC大类 C12（42） G01（22） B82（8）
C01（6） B01（3） C25（2）
H01（2）
IPC小类 C12Q（42）
IPC C12Q001/68（42）
发明人 ZHANG Y（3） CHEN Q（2） DENG T（2）
FAN Q（2） GOLOVCHENKO J（2） GOLOVCHENKO J A（2）
HOU J（2） LI J（2） LI Z（2）
LIU X（2） LIU Y（2） NIU X（2）
PENG H（2） SUN W（2） WANG H（2）
公开年 2017（10） 2016（8） 2012（5） 2013（5） 2015（5） 2014（4）
申请年 2016（11）  2012（6）  2015（6）  2014（5）  2017（5）  2010（2）  2011（2）  2013（2） 
专利权人 CAPITALBIO G.（2） HARVARD COLL.（2） INT BUSINESS.（2） SHANGHAI INS.（2）
UNIV BEIJING.（2） UNIV HAINAN .（2） UNIV TSINGHU.（2）

Argonaute protein-based field effect transistor nucleic acid sensor comprises insulating substrate, ultra-thin semiconductor material layer arranged on an insulating substrate, and source and drain electrodes are set at both ends of the ultra-thin semiconductor material layer.

KONG D, WEI D

Detecting disease state in a subject comprises e.g. obtaining liquid biological sample from the subject and placing it into a container, contacting the liquid biological sample with a first chemical sensor element, and sensing.

ROGNRUD C B, KOYA V, JUDISCH A, TASSONI A F, SHERWOOD G J, FROST K L, NELSON J T

Producing sequencing unit useful for sequencing biochemical material, comprises creating sequencing pore for sequencing biochemical material in precursor layer by thermal lithography and converting pre-structured layer to graphene layer.

LAERMER F

Graphene transistor-based DNA sensor useful for DNA detection, comprises e.g. an electronic-grade glass, a grid, source electrode, drain electrode and single-stranded DNA.

LI J, LI S, HUANG K, FAN Q, WANG X

Optical fiber FET biosensor used in biological testing device, has graphene film whose surface is fixed with single-stranded deoxyribonucleic acid (DNA) as probe chain whose end modifies fluorescent dye.

YUE W, XIE X, TANG C, HUA H, ZHANG Z, LI J

Desorption of micro RNA from graphene comprises in situ reverse transcription reacting graphene.

XING W, YAN H

Gene sequencing chip of gene sequencing device, has first electrode and second electrode which are configured to detect resistance of graphene oxide layer.

PANG F, CHE C, XUE H, SHAO X, CAI P

Solid phase extraction material useful in kit for performing enrichment or detection of nucleic acids, comprises solid phase substrate surface modified graphene oxide or reduced graphene oxide.

LU Y, XING W, YAN H

Nucleic acid detection device for detecting or discriminating nucleic acid having one or more mismatches, comprises graphene chip, double-stranded nucleic acid probe, and microcontroller board that comprises digital meter.

GLINSKII G V, HWANG M T, LAL R, LANDON P B, LEE J, MECKES B, MO A, RAMACHANDRAN S, LI Z

Detecting sulfonated graphene useful for distinguishing between single base mismatched DNA and target DNA strand by adding e.g. target DNA to trisaminomethane-hydrochloric acid buffer, reacting and measuring e.g. fluorescence intensity.

CHEN W, WANG Y, DENG H, PENG H, LIN X