国家/地区 美国（19）
IPC部 C（19）
IPC大类 C12（19） G01（17） B01（5）
A61（3） H01（3） B03（2）
B81（2）
IPC小类 C12Q（19）
IPC G01N033/543（7） G01N027/414（6） B01L003/00（5）
C12Q001/6869（4） C12Q001/6825（3） G01N027/327（3）
G01N033/53（3） G01N033/569（3） G01N033/574（3）
A61K047/69（2） A61K049/00（2） B03C001/015（2）
B03C001/30（2） C12M001/34（2） C12Q001/00（2）
发明人 SUGIZAKI Y（3） HE M（2）
公开年 2021（12） 2022（7）
申请年 2021（19）
专利权人 TOSHIBA CORP（3） TOSHIBA KK（3） UNIV KANSAS（2） UNIV KANSAS .（2）

Forming a conductive material nanogap used in macromolecule translocation device, involves providing a base material, applying conductive material sheet to first layered material, applying two conducting electrodes to material sheet, applying passivation layer over etch mask, and fabricating hole.

POSTMA H

Analyzing target particle in specimen involves dispensing specimen into first containers configured to capture target particle, removing contaminant other than target particle to be captured from specimen, adding probes to containers and amplifying the reporter portion by using common primer set.

SUGIZAKI Y

Chemical sensor device comprises sensor element, oligopeptide mounted on surface of sensor element and containing first peptide sequence forming beta-sheet structure and cysteine residue at position different from first peptide sequence, and probe bonded to cysteine and binds to specific substance.

ISOBAYASHI A, SUGIZAKI Y, MIKI H

Forming substrate for detection of analyte molecule in sample involves providing base layer, providing binding layer on base layer, depositing top layer on binding layer, patterning top layer to expose portions of binding layer, and providing supramolecular structure.

BOWEN S, SHETTY R, ROTHEMUND P, GOPINATH A

System for analyzing of sample, where sample comprises bio-molecules comprises nano array, that comprises substrate, where substrate is glass, and multiple of plasmonic metal protrusions extending from substrate, where multiple of plasmonic metal protrusions is of plasmonic metal that is gold.

YANG L, LEE K

Sensor for detecting target substance in gas sample has target substance uptake unit, and reaction unit holding acetylcholinesterase and brings solution delivered from target substance uptake unit into contact with acetylcholinesterase.

SUGIZAKI Y, SAITO T

Composition used to isolate extracellular vesicle, comprises many magnetic particles, each magnetic particle comprising core particle and targeting moiety extending from the core particle via photocleavable linker.

HE M

Working electrode used for subcutaneous sensor for use with continuous biological monitor for patient, comprises conductive substrate, and carbon-enzyme layer on conductive substrate, where carbon-enzyme layer comprises polyurethane crosslinked with acrylic polyol, and enzyme fully entrapped.

ZHANG H, BOOCK R J

Device for amplifying and detecting gene, comprises gene amplification chip comprising channels through which sample flows, transparent heaters comprising graphene layer provided on metal thin-film layer, and insulating hole.

CHUNG K H, KIM J T, CHUNG K

Integrated circuit chip for electronic biological sample analysis has chemically differentiated array of graphene field effect transistors, and biomolecules (selected to bind to biological substance) that functionalize graphene channels.

GOLDSMITH B